Mast Cells

Definition of Mast Cells:

These are a group of cells that line the capillaries of tissues that come in contact with the outside, for example skin, sinuses, and lung mucosa.  They, like their first cousin basophils, are produced in the red bone marrow and migrate to the appropriate tissues, where they stay.  They bind IgE, supply the histamine and heparin response that gives you a healing inflammation, and cause allergies.

Also: Mast Cell

Topics Related to Mast Cells

Allergic Conjunctivitis

...the condition
“...Signs and Symptoms: Symptoms are due to release of histamine and other active substances by mast cells and may include red eyes, dilated vessels in the clear tissue covering the whites of the eyes, itching and/or burning eyes, swollen eyelids, watery eyes, or stringy eye discharge...”

Allergic Rhinitis / Hay Fever

...recommendation Bioflavonoids
“...Quercetin appears to stabilize the membranes of the mast cells that release histamine...”
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More topics Related to Mast Cells

Allergy to Foods (Hidden)

...our question about Pain in the upper abdomen / stomach area
“...Sometimes mast cells are involved in allergic reactions and release chemicals such as histamine...”

Heparin

...as a treatment
“Heparin is a naturally-occurring anticoagulant produced by basophils and mast cells...”

Histamine Therapy

...as a treatment
“...In many cases, the lymphocyte triggered to respond is a mast cell...”

Hives (Urticaria)

...the condition
“...The reaction involves the release of histamine from either mast cells or basophils causing an IgE (immediate type) mediated antibody response...”
...relationship to Autoimmune Tendency
“...hives have an autoimmune origin which means, in about 30% of patients, that the immune system is producing antibodies against normal substances in the body and triggering the release of histamine by mast cells...”
...recommendation Conventional Drug Use
“...This is because in people with hives, histamine is being released by mast cells in the tissues which in turn initiates the irritation and accumulations of fluid...”
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More topics Related to Mast Cells

IgE

...related topic
“...IgE travels to mast cells, sticks to their surfaces, and when antigens get stuck to the IgE, the mast cells secrete inflammatory compounds such as histamine...”

Mastocytosis

...the condition
“Mastocytosis is a disorder characterized by mast cell proliferation and accumulation within various organs, most commonly the skin...”

Test for Inhalant Allergies

...as a treatment
“...Upon encountering an allergen, IgE activates special cells called mast cells, which in turn release chemicals called mediators – such as histamine, the chemical that causes redness and swelling...”

Tylophora

...as a treatment
“...] Test tube studies suggest that tylophorine is able to interfere with the action of mast cells, which are key components in the process of inflammation...”
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