Bilirubin

Definition of Bilirubin:

A waste product of hemoglobin recycling, it is primarily excreted in feces, oxidizing into that familiar brown color (except for beets).

Topics Related to Bilirubin

Bile Duct Cancer

...the condition
“...Jaundice is caused by the accumulation in the skin of a component of bile (bilirubin) that normally empties into the intestines after traveling through the bile ducts...”

Bilirubinemia

...related topic
“The presence of abnormally high bilirubin in the blood, usually signifying hepatitis, with jaundice due next week.”
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More topics Related to Bilirubin

Bilirubinuria

...related topic
“Presence of bilirubin (yellow-red pigment of bile) in urine.”

Cirrhosis of the Liver

...the condition
“...Tests can reveal liver problems including ... Elevated bilirubin...”

Crohn's Disease

...the condition
“...Increased alkaline phosphatase, serum glutamic-oxaloacetic transminase (SGOT) (AST {aspartate aminotransferase}) or bilirubin due to associated liver disease...”

Elevated Bilirubin Levels

...the condition
Bilirubin is produced when the liver breaks down old red blood cells...”
...relationship to Hemolytic Anemia
“Certain conditions, such as hemolytic anemia, can cause increased destruction of red blood cells and therefore increased bilirubin production.”
...relationship to Hepatitis
“Diseases that cause liver damage can lead to increased bilirubin levels.  To further investigate the cause of jaundice or increased bilirubin levels, liver function tests or other evidence of infective hepatitis (hepatitis A, B, C, delta, E, etc...”
...relationship to Cirrhosis of the Liver
“Diseases that cause liver damage can lead to increased bilirubin levels.  Cirrhosis may cause normal, moderately high or high levels of bilirubin, depending on the type of cirrhosis.”
...relationship to Sickle Cell Trait / Disease
“Sickle cell disease causes rapid destruction of red blood cells in the blood, leading to increased bilirubin levels.”
...relationship to Gilbert's Syndrome
“One common – and harmless – cause of elevated bilirubin is Gilbert's syndrome, a deficiency in an enzyme that helps break down bilirubin.”

Gallbladder Cancer

...the condition
“...Blood tests are used to test liver and gallbladder function, and measure how much bilirubin is in the blood, as well as albumin, alkaline phosphatase, AST, ALT, and GGT, which can all be at abnormal levels in cases of liver, bile duct, or gallbladder disease...”

Gallbladder Disease

...the condition
“...They are composed of calcium bilirubinate, or calcified bilirubin, the substance formed by the breakdown of hemoglobin in the blood...”

Gilbert's Syndrome

...the condition
“Gilbert's Syndrome, characterized by a chronically elevated serum bilirubin level (1.2 to 3.0mg/dL), is the most common of all benign unconjugated hyper-bilirubinemias...”
...recommendation Fluoride Reduction/Avoidance
“John Lee, MD, a physician in private practice has stated that elevated bilirubin levels can be reduced in Gilbert's syndrome by avoiding fluoridated water and other sources of fluoride...”
...recommendation TMG (Trimethylglycine)
“Methionine, administered as SAM, resulted in a significant decreases in serum bilirubin in patients with Gilbert's syndrome in a recent clinical study...”
...recommendation Methionine
“Methionine, administered as SAM, resulted in a significant decreases in serum bilirubin in patients with Gilbert's syndrome in a recent clinical study...”
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More topics Related to Bilirubin

Hepatitis

...our question about Yellow skin tone
“Hepatitis is an inflammation of the liver that often causes the kidneys to excrete high levels of bilirubin into the bloodstream, leading to a yellow discoloration of the skin...”

Jaundice

...the condition
“...(from the French word jaune, meaning yellow) is an abnormal condition in which the body fluids and tissues, particularly the skin and eyes, take on a yellowish color as a result of an excess of bilirubin.  It is important to recognize that jaundice itself is not a disease, but rather a symptom of an underlying pathological process that occurs at some point along the normal physiological...”
...related topic
“Yellow discoloration of the skin, whites of the eyes and excreta as a result of an excess of the pigment bilirubin in the bloodstream.”
...relationship to Gallbladder Disease
“...When gallstones are obstructing these ducts, bile builds up in the gallbladder and increases the concentration of a yellowish substance called bilirubin in the blood, causing a yellowing of the skin known as jaundice.”
...relationship to Cirrhosis of the Liver
“Jaundice is a yellowing of the skin and eyes that occurs when the diseased liver does not process enough bilirubin.”
...relationship to Hepatitis
“Jaundice is a yellow discoloration of the skin and whites of the eyes caused by increased amounts of bilirubin in the bloodstream...”

Liver Function Test Requirement

...the condition
“...The most commonly performed blood tests include ... Serum Bilirubin Test.  Elevated levels of bilirubin often indicate an obstruction of bile flow or a defect in the processing of bile by the liver...”

Need For Routine Preventative Health Measures

...the condition
“...Important preventable risk factors can be identified through monitoring various blood components such as albumin, alkaline phosphatase, bilirubin/total, blood urea nitrogen, calcium and phosphorus, cholesterol, coronary risk factor, creatinine, GGT/LDH, globulin and glucose...”

Ulcerative Colitis

...the condition
“...Laboratory findings ... Increased alkaline phosphatase, SGOT (AST) and bilirubin due to associated liver disease...”

Urinalysis

...as a treatment
“...The urinalysis may be inaccurate if the sample is over 1 hour old due to changes which occur ... loss of bilirubin...”

Vitamin E Requirement

...the condition
“...Signs and symptoms include dry skin, easy bruising, decreased clotting time, eczema, elevated indirect bilirubin, psoriasis, elevated heavy metals, PMS, cystic fibrosis, sickle cell anemia, beta thalassemia, cataracts, fibrocystic disease, benign prostatic hypertrophy, poor wound healing, hot flashes...”
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