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Coronary Disease /
Heart Attack
  Heart Attack / Coronary Disease
 Signs, symptoms, indicators
 Conditions that suggest it
 Contributing risk factors
 Conditions suggested by it
 It can lead to...
 Treatment recommendations
 Prevention
 


Irreversible and unexpected, heart failure is the leading cause of death in Western countries. For 50% of men who die from heart attacks, the fatal attack is their first symptom. Coronary artery disease (heart attack, or myocardial infarction) is the number one killer in the United States, yet it barely existed before 1900. A sampling of older cardiologists still working in the 1950s could not recall a case prior to 1910. Most people are unaware of this and do not readily believe it. It is not a highly publicized fact, possibly because it glaringly reminds us of the cause: the way we now live, principally the westernization of diet (the consumption of commercially processed foods). Some take a position that people were more active then, and we are more sedentary now. This is true, but should not be used as an excuse to continue eating what we prefer, instead of what we should. The high prevalence of cardiovascular disease (CVD) is a major health concern for both health authorities and the general population. It is a leading cause of death and results in a considerable burden, in terms of illness, disability and economic costs.

Holistic/alternative doctors are now talking about and distinguishing between two types of plaque. Type 1 is commonly associated with artery obstruction (though it is more stable and new collateral circulation develops). Type 2 causes only minimal occlusion. Unexpectedly, Type 2 appears to be responsible for as much as 80% of heart disease and strokes. This type of plaque, though not blocking the blood flow is dangerous because it has a looser fibrin coat, and a tendency to be more reactive. The treatment goal is to make it less reactive, to in effect turn it from Velcro to Teflon.

Incidence; Risk Factors


There is a general misconception that CVD affects only men, leading women to believe that they are not at risk. Although CVD is more prevalent in men, it is not a gender-specific health problem. Between 40 and 59 years of age, as many as 1 in 12 women display clinical evidence of heart disease. This prevalence rises to 1 in 3 among women older than 65.

Although mortality due to CVD is declining due to advances in prevention and treatment, the risk of developing CVD continues to be a concern due to the significant prevalence of modifiable risk factors such as cigarette smoking, high blood pressure, high blood cholesterol levels, poor diet, obesity and limited physical activity. Many other risk factors can be reduced once they have been tested for. Laboratory testing is now going far beyond total cholesterol (HCL and LDL ratios) and triglycerides. Anyone with an elevated risk of heart disease should do specific testing to assess their risk and make the necessary changes. Such tests include hs-CRP, lipoprotein(a), homocysteine and fibrinogen among others.

Treatment & Prevention
Coronary artery bypass surgery is one of the most widely performed and often unnecessary surgeries in the United States. While the surgery does increase long-term survival of those with the most severe forms (left main coronary artery occlusion and three-vessel disease) and gives relief of symptoms for 85%, the long-term results actually indicate a reduced survival rate for those with mild to moderate coronary artery disease and a return of symptoms within five years. Complications arising from coronary bypass operations are common, as this surgery represents one of the most technically difficult procedures in modern medicine.





Signs, symptoms & indicators of Coronary Disease / Heart Attack:
Lab Values - Chemistries  High uric acid level
 Elevated levels of serum uric acid increase the risk of heart attack.

In evaluating 5,926 subjects who were between 25 and 74 years of age, after 16.4 years of follow-up, there were 1,593 deaths of which 45.9% were attributed to cardiovascular disease. It was found that increased serum uric acid levels were independently and significantly associated with the risk of cardiovascular mortality. [JAMA, May 10, 2000;283(18): pp.2404-2410]

Lab Values - Common

  Rapid pulse rate
 Heart rate is a stronger predictor of cardiovascular death in the elderly, particularly in men, than traditional risk factors such as diabetes and hypertension. Elderly men with a pulse rate above 80 beats per minute have a significantly higher rate of cardiovascular mortality. A low heart rate, below 64 beats per minute, is protective against cardiovascular mortality.


Counter-indicators:
  Slowed pulse rate
 Heart rate is a stronger predictor of cardiovascular death in the elderly, particularly in men, than traditional risk factors such as diabetes and hypertension. Elderly men with a pulse rate above 80 beats per minute have a significantly higher rate of cardiovascular mortality. A low heart rate, below 64 beats per minute, is protective against cardiovascular mortality.

Symptoms - Bowel Movements

  Undigested fat in stools
 In one study, subjects with heart disease had 10 times more fat in their stool than heart-healthy individuals. This means those with heart disease weren’t absorbing their fats [Am J Cardiology 5: p.295, 1960].

Symptoms - Cardiovascular

  Pain in chest or left side

Symptoms - Head - Ears

  Diagonal creases on earlobes
 The presence of a diagonal earlobe crease has been recognized as a sign of cardiovascular disease since 1973. Over 30 subsequent studies have been reported in the medical literature, with the largest involving 1,000 unselected patients. The earlobe is richly supplied with blood, and a decrease in flow over an extended period of time is believed to result in collapse of the vascular bed, leading to a diagonal crease.

It appears that individuals with an earlobe crease have a 55% greater risk of dying from heart disease than those without the marking, with the risk becoming even more significant if diagonal creases appear on both earlobes. However, this predictive value does not apply to Orientals, Native Americans, or persons born with certain hereditary disorders.

Symptoms - Metabolic

  Very great/major/moderate unexplained weight loss
 Weight loss is a common finding among individuals with chronic heart failure. It is evident that malabsorption of fats is related to heart failure. In one study, subjects with heart disease had 10 times more fat in their stool than heart-healthy individuals. This means those with heart disease weren’t absorbing their fats [Am J Cardiology 5: p.295, 1960]. Yet heart patients are typically placed on low-fat diets! These individuals were leaner, but not healthier.

Symptoms - Mind - Emotional

  Impatient/hostile disposition
 People who are highly anger-prone are nearly three times more likely to have heart attacks according to a study in the May 2, 2000 issue of Circulation. The study adds to previous research showing a link to heart health and other emotions, such as depression and hostility.

Symptoms - Respiratory

  (Sudden) shortness of breath

Conditions that suggest Coronary Disease / Heart Attack:
Circulation  Pulmonary Embolism

Habits

  Excessive Yawning
 Excessive yawning can be caused by a vasovagal reaction and may indicate a heart problem.

Lab Values

  Hypoalbuminemia (A low albumin level)

Lab Values - Common

  Recent onset/medium-term/long-term hypertension
 While systolic blood pressure is a better predictor of cardiovascular events than diastolic blood pressure or pulse pressure, all three measures are strongly and directly related to the risk of coronary and cerebrovascular events. [Archives of Internal Medicine, 2001; 161: pp.1183-92]

Respiratory

  Obstructive Sleep Apnea (OSA)
 Obstructive sleep apnea is a significant risk factor for myocardial infarction.

Skin-Hair-Nails

  Male Hair Loss
 A Harvard study found that male-pattern baldness may be a marker for increased risk of coronary heart disease. Severe hair loss on the top of head resulted in a 36% increased risk. The risk became lower with less hair loss. [Archives of Internal Medicine, Jan. 24, 2001]

Uro-Genital

  Erectile Dysfunction (ED, Impotence)
 A long-running study of over 2,000 men found that erectile dysfunction is associated with a more than threefold higher risk of heart attack. Lead researcher Dr. Steven J. Jacobsen, a professor of epidemiology at the Mayo Clinic, reported the findings Nov. 11, 2003 at the American Heart Association's annual conference in Orlando, Florida. According to Jacobsen, "We can't say that it is cause-and-effect, but erectile dysfunction is a marker for future events of cardiovascular disease." Overall, men with a heart attack from 1979 to 1995 were 3.5 times more likely to have erectile dysfunction in 1996 than men who did not have a heart attack.

Risk factors for Coronary Disease / Heart Attack:
Addictions  Cigarette Smoke Damage
 According to a report from the U.S. Surgeon General, "Cigarette smoking should be considered the most important risk factor for coronary heart disease." Statistical evidence reveals a three- to five-fold increase in the risk of coronary artery disease in smokers compared to nonsmokers. Risk of dying from a heart attack or stroke depends the number of cigarettes smoked, the number of years smoked, the age of smoking onset and depth of inhalation. However, when a woman stops smoking, no matter how long or how much she smoked, her risk of heart disease drops by 50% in the first year alone. Similar benefits would be expected for a man.

  Cocaine Addiction
 In 1999 the Journal of the American Medical Association reported that the risk of death from a heart attack rose 24-fold in the first hour after cocaine use.

Circulation

  Angina
  Poor Circulation
 Not everyone with heart disease gets peripheral vascular disease, and vice versa. For some reason, the process of atherosclerosis seems to affect different people in different places. However, if you have one, you are definitely at increased risk for the other.

Diet

  Salt Sensitivity
 People who experience a jump in blood pressure when they consume salt are at increased risk of dying from heart disease. Even salt-sensitive individuals with normal blood pressure are at risk, as blood pressure eventually rises. [Hypertension (supp), Feb. 16, 2001] Hypertension and salt sensitivity are independent risk factors for cardiovascular disease.

  Dehydration

Family History

  Heart attack(s) in mother
  Heart attack(s) in father

Habits

  Problems Associated With Lack Of Exercise
 Because it increases the risk for coronary artery disease by almost two times, a lack of exercise is nearly as dangerous to the heart as smoking, abnormal cholesterol levels, or hypertension. Sedentary living is the fourth major cardiac risk factor.

Hormones

  Low Male Testosterone Level
 Researchers at Columbia University Medical School studied 55 men undergoing X-ray exams of their arteries and found that those with a lower testosterone level had higher degrees of heart disease (blockage of the coronary arteries). This study also found that the protective HDL cholesterol levels were higher in men with higher testosterone levels.

Low testosterone is linked to hypertension, obesity, atherosclerosis and increased waist-to-hip ratio - all of these being heart attack risk factors. Administration of testosterone to men has been reported to decrease the risk factors for heart attack.

Lab Values

  Elevated Homocysteine Levels
 Elevated homocysteine levels are believed to exacerbate oxidative injury to blood vessels and increase pro-clotting mechanisms linked to stroke and heart attack.

  High Total Cholesterol
  High Levels Of Triglycerides
 There are a group of studies clearly indicating that elevated triglycerides combined with low HDL (two abnormalities known to be caused by high insulin) are much more predictive of cardiovascular disease than either elevated total cholesterol or elevated LDL levels.

Lab Values - Chemistries

  (Very) low HDL level
  (Very) high LDL

Counter-indicators:
  Optimal LDL
  Excellent HDL level

Medications

  Birth Control Pill Issues
 If you smoke, it should be noted that there is a synergistic effect between smoking, oral contraceptives and the risk of cardiovascular disease.

Mental

  Depression
 While previous research has shown that depression in men and women is linked to heart disease, a recent study found that only men who are depressed face an increased risk of heart disease-related death. [Archives of Internal Medicine, May 8, 2000)]

  Stress
 Stress may increase magnesium excretion and the resulting temporary magnesium depletion may make the heart more sensitive to electrical abnormalities and vascular spasm that could lead to cardiac ischemia.

Metabolic

  Problems Caused By Being Overweight
 Even if you never become diabetic, high levels of insulin contribute to cardiovascular risk by increasing the process of atherosclerosis. Insulin increases the rate at which cholesterol-laden plaque builds up on arterial walls. The abnormally high levels of insulin produced by all overweight individuals, diabetic or not, is an independent risk factor for early cardiac death.

  Anorexia / Starvation Tendency
 Being severely underweight can cause heart failure.

  Hemochromatosis (Iron overload)
 Male carriers of the common hemochromatosis gene mutation are at 2-fold risk of a first heart attack compared with noncarriers. Some 10% to 20% of the population carry at least one gene for hemochromatosis. Full-blown hemochromatosis affects about 0.5% and gene carriers usually do not know that they are at increased risk. They have almost no increase in iron stores over those without the mutation [Circulation: Journal of the American Heart Association September 21, 1999;100].

Giving blood is the best way to lower iron stores, but a more recent study found no protective effect against heart attack among men who donated blood regularly. [Circulation January 2, 2001]

Musculo-Skeletal

  Gout / Hyperuricemia
 Elevated uric acid levels, as seen in gout, may be associated with a higher incidence of coronary heart disease amongst alcohol abstainers, but has not been seen to occur in those who were light, moderate or heavy drinkers. [ Journal of Clinical Epidemiology,1996;49(6) pp.673-678]

Nutrients

  EFA (Essential Fatty Acid) Type 3 Requirement
 Many studies have shown that higher omega-3 fatty acid intake can cut the rate of sudden cardiac death by nearly one-half, in both apparently healthy patients and those who have suffered a previous heart attack.

To better understand this protective effect, Danish researchers examined the dietary patterns and individual fatty acid status of nearly 300 patients with ischemic heart disease, comparing them with specific parameters of cardiac function. They found that the patients who ate more fish had higher levels of omega-3 polyunsaturated fats in their blood cell membranes and in their fat cells. A higher level of two specific fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) - especially within the cell membrane - was associated with higher heart rate variability in the patients. An increased heart rate variability indicates healthier pulse regulation, and appears to significantly reduce the risk of arrhythmia and cardiac death.

Organ Health

  Diabetes Type II
 Cardiovascular disease is the leading cause of diabetes-related death. People with diabetes are two to four times more likely to develop cardiovascular disease. At least 65% of people with diabetes die from heart disease or stroke.

  Diabetes Type 1.5
 It is not clear yet if people with type 1.5 have the same high risk for cardiovascular problems as individuals with type 2.

Personal Background

  African ethnicity
 African-Americans have higher rates of diabetes, prostate cancer, hypertension and coronary heart disease than whites.

Supplements and Medications

  Current birth control pill use
 Statistics now show that the wide use of the Pill has given rise to health hazards such as breast cancer, high blood pressure and cardiovascular disease that were previously unrecognized.

  History of birth control pill use

Symptoms - Cardiovascular

  History of/history of severe heart attack or history of heart attacks

Symptoms - Food - Beverages

Counter-indicators:
  Moderate/low alcohol consumption
 Drinking in moderation has been linked with a lower risk of having a fatal heart attack. [Journal of the American Medical Association April 18, 2001; 285: pp.1965-1977]

Symptoms - Food - General

  Long-term/short-term low-carb dieting
 Essentially every single study on low carbohydrate diets that measured uric acid levels has shown that uric acid levels rose. [Obesity Research 9 (2001): p.1s] Uric acid itself has been tied to cardiovascular disease risk in virtually every instance it's been studied over the last 50 years, and may be an independent risk factor by increasing free radical damage or making the blood more susceptible to clotting. [American Journal of Cardiology 85 (2000): p.1018]

In another clinical trial, despite statistically significant weight loss reported in the Atkins group, every single cardiac risk factor measured worsened after a year on the Atkins Diet (measures included LDL, triglycerides, total cholesterol, HDL, total-to-HDL cholesterol ratio, homocysteine, Lp(a), and fibrinogen). While the LDL in the Atkins group increased 6%, the LDL cholesterol levels in the whole-foods vegetarian group was cut in half - dropping 52%.

Based on an analysis of the Atkins Diet, long-term use of the Atkins Diet is expected to raise coronary heart disease risk by over 50%. [Journal of the American College of nutrition 19 (2000): p.578]

Symptoms - Food - Intake

Counter-indicators:
  Moderate/high fruit/vegetable consumption
  Moderate/high legume consumption
 Men and women who ate legumes at least four times a week were found to have a 22% lower risk of coronary heart disease over 19 years than those who consumed legumes once weekly, researchers report in the November 26th issue of the Archives of Internal Medicine. The study was based on interviews and medical exams of more than 9,600 Americans who did not have heart disease when the study began. [Archives of Internal Medicine 2001;161: pp.2573-8].

Symptoms - Metabolic

  Apple-shaped body when overweight

Uro-Genital

  Polycystic Ovary Syndrome (PCOS)
 Women with the PCOS have a five to seven times higher risk of myocardial infarction and ischemic heart disease than other women. Surprisingly, the increased risk was found to be independent of obesity, supporting the argument that insulin resistance alone is important in determining cardiovascular risk. [Fertil Steril 2000;73(1): pp.150-156, J Clin Endocrinol Metab 1999;84(6): pp.1897-1899]

Coronary Disease / Heart Attack suggests the following may be present:
Circulation  Angina

Metabolic

  Anorexia / Starvation Tendency
 Being severely underweight can cause heart failure.

  Problems Caused By Being Overweight
 Even if you never become diabetic, high levels of insulin contribute to cardiovascular risk by increasing the process of atherosclerosis. Insulin increases the rate at which cholesterol-laden plaque builds up on arterial walls. The abnormally high levels of insulin produced by all overweight individuals, diabetic or not, is an independent risk factor for early cardiac death.

Coronary Disease / Heart Attack can lead to:
Digestion  Dyspepsia / Poor Digestion

Recommendations and treatments for Coronary Disease / Heart Attack:
Amino Acid / Protein  L-Proline
 See links between Increased Risk of Heart Attack and the treatments Lysine and Vitamin C.

  L-Lysine
 Linus Pauling discovered that supplemental L-lysine reduces the binding of lipoprotein-a, also known as Lp(a), in its binding to the walls of arteries. By preventing this action, plaque buildup is discouraged since plaque is made up primarily of Lp(a). The naturally occurring amino acids lysine and proline assist Lp(a) in its deposition and binding to stressed or injured vascular wall sites. However, when there is an extra quantity of lysine and proline in the blood stream, the Lp(a) attachment sites get blocked by these amino acids creating a "Teflon-like" layer around the lipoprotein particles. This prevents the Lp(a) from binding to artery walls, as well as helps detach Lp(a) plaque from preexisting sites in the vascular wall. This supplemental use of these amino acids can prevent plaque build-up and initiate the reversal of plaque deposits. The amount will vary between individuals. Seriously ill heart patients require 5-6 grams (5,000 to 6,000mg) of lysine daily. This strategy may be useful for treating type 2 plaque.

  Cysteine / N-Acetyl-Cysteine (NAC)
 Cysteine is sometimes used to help lessen the risk of coronary artery disease.

Botanical

  Garlic

Detoxification

  Chelation Therapy

Diet

  Animal/Saturated Fats Avoidance
 Where heart disease is concerned, animal fats are generally considered unhealthy due to their association with high cholesterol levels in the blood.

  Weight Loss
  Increased Water Consumption
 A Seventh Day Adventist study found that those who drank 5 glasses of water per day have on average half the cardiac mortality and half the fatal stroke rate of the general population.

  Therapeutic Fasting
  Low/Decreased Fat Diet
  Caffeine/Coffee Avoidance
 Coffee, including decaf, contains significant amounts of Vitamin K which is an important factor for blood coagulation. People at high risk for blood clots, strokes, and heart attacks should avoid coffee and decaf for this reason.

  Monounsaturated Oils
 The use of monounsaturated oils such as olive oil may be more protective than a low fat diet. Use olive oil or coconut oil exclusively when frying. Avoid the use of hydrogenated fats (they contain trans-fatty acids) which may be worse than saturated fats in contributing to heart disease.

Extract

  Policosanol/Octacosanol
 Policosanol has other actions against heart disease in addition to lowering cholesterol. Like statin drugs, policosanol helps stop the formation of arterial lesions. One of policosanol’s important actions is to inhibit the oxidation of LDL, which is the major contributor to arterial damage. Oxidized LDL promotes the destruction of blood vessels by creating a chronic inflammatory response.

Habits

  Tobacco Avoidance

Hormone

  DHEA
 A landmark study in 1986 of 242 men aged 50-79 and based on 12 years of research stated that a small supplementation of DHEA corresponded to a 48% reduction in death from heart disease and a 36% reduction in death from any cause, other than accidents. Indirect evidence does suggest that DHEA supplements might reduce the risk of heart disease, especially in men, but this is far from proven.

Lab Tests/Rule-Outs

  Test for Cardiac Risk Factors
  Bacteria / Pathogen Testing by PCR
 US Biotek lab offers a Cardiovascular Disease Panel (Blood or Tissue Biopsy) which tests for the presence of Chlamydia pneumoniae, Mycoplasma pneumoniae, Helicobacter pylori, Cytomegalovirus (CMV) and Human Herpes Virus 6 (HHV-6).

Mineral

  Selenium
 Selenium is considered to be from 200 to 500 times more potent an antioxidant than Vitamin E. Selenium and Vitamin E are synergistic as antioxidants and inhibit or prevent the damage to tissues by free radicals which have been cited as causal factors in heart disease.

  Magnesium
  Potassium

Nutrient

  Essential Fatty Acids
 Many studies have shown that higher omega-3 fatty acid intake, through fish consumption or through supplementation, can cut the rate of sudden cardiac death by nearly one-half, in both apparently healthy patients and those who have suffered a previous heart attack.

To better understand this protective effect, Danish researchers examined the dietary patterns and individual fatty acid status of nearly 300 patients with ischemic heart disease, comparing them with specific parameters of cardiac function. They found that the patients who ate more fish had higher levels of omega-3 polyunsaturated fats in their blood cell membranes and in their fat cells. A higher level of two specific fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) - especially within the cell membrane - was associated with higher heart rate variability in the patients. An increased heart rate variability indicates healthier pulse regulation, and appears to significantly reduce the risk of arrhythmia and cardiac death.

Anti-inflammatory agents such as the omega-3 oils are especially useful when inflammation is present. [Circulation 2001;104(19): pp.2269-2272]

Oxygen / Oxidative Therapies

  Ozone / Oxidative Therapy
 If infection is present, selected antibiotic therapies such as UV blood irradiation or oxidative therapies (H2O2/ozone) can reduce the risk associated with certain infections.

Physical Medicine

  Pressure
 Aside from CPR and dialing 911, there may be additional measures one can take when a heart attack occurs. Without help, a person whose heart stops beating properly and who begins to feel faint has only about 10 seconds left before losing consciousness.

These victims can help themselves by coughing repeatedly and vigorously. A deep breath should be taken before each cough, and the cough must be deep and prolonged, as when producing sputum from deep inside the chest. A breath and a cough must be repeated about every two seconds, non-stop until help arrives or until the heart is felt to be beating normally again. Deep breaths get oxygen into the lungs and coughing movements squeeze the heart and keep the blood circulating. Some claim that biting or stimulating the tips of the little fingers (heart meridian) can provide needed stimulation at this critical time, and improve the prospects of recovery.

Psychological

  Stress Management
 People who live in a chronically stressed-out condition are more likely to take up smoking, frequently overeat, and be far less likely to exercise. All of these stress-related behaviors have a direct effect on the development of coronary artery disease.

It is also known that the surge in adrenaline caused by severe emotional stress causes the blood to clot more readily (a major factor in heart attacks) and that the stress of performing difficult arithmetic problems can constrict the coronary arteries in such a way that blood flow to the heart muscle is reduced. Stress increases homocysteine levels, a known risk factor for coronary artery disease.

Surgery/Invasive

  Angioplasty

Vitamins

  Vitamin C (Ascorbic Acid)
 Supplemental vitamin C can help heal injured arteries when used with L-lysine and proline for plaque prevention and possibly removal. A typical prescription would be 3-6gm vitamin C, 3-6gm lysine and 0.5-2gm proline. Furthermore, vitamin C deficiency (as indicated by low plasma ascorbate concentration) is a known risk factor for coronary heart disease.

One year of supplementation with vitamin C (500mg bid) and vitamin E (400 IU bid) retarded the early progression of
transplant-associated coronary arteriosclerosis in a study of 40 patients up to 2 years after cardiac transplantation. [Lancet 2002;359(9312): pp.1108-13]

Vitamin C treatment has a possible role in benefiting patients with coronary heart disease by countering the adverse effects of a high-fat meal. Researchers found that postprandial serum triglyceride concentration increased significantly at 2-5 hours after a high-fat meal in all groups. The postprandial flow-mediated dilatation was significantly aggravated in people not taking vitamin C (both with and without heart disease), but this parameter in patients and subjects taking vitamin C showed no significant change. [Clin Cardiol 2002;25: pp.219-224]

  Vitamin B6 (Pyridoxine)
 It is estimated that individuals with low vitamin B6 levels have a five times greater risk of suffering a heart attack than individuals with higher B6 levels.

  Vitamin B-Complex
 105 male and female subjects with coronary artery disease who received folic acid (1mg/day), vitamin B12 (400mcg/day) and vitamin B6 (10mg/day) experienced a significant reduction in reblockage after angioplasty over those who did not take the vitamins. Homocysteine levels were reduced during the trial. [N Engl J Med November 29, 2001;345: pp.1593-1601]

Preventive measures against Coronary Disease / Heart Attack:
BotanicalNot recommended:
  Marijuana
 The risk of a heart attack jumps nearly five-fold during the first hour after smoking marijuana, posing a particular threat to middle-aged users of the drug, according to a study in 2001. Starting in the third hour after smoking marijuana, no significant risk rise was documented.

Diet

  Nut and Seed Consumption
 A Seventh Day Adventist study that was reported at the 2002 International Congress on Vegetarian Nutrition found those that ate a serving of nuts 5 times per week had half the cardiac mortality.

  Increased Legume Consumption
 Bulking up the diet with legumes such as beans and peas can lower the risk of heart disease, study findings suggest. Men and women who ate legumes at least four times a week were found to have a 22% lower risk of coronary heart disease over 19 years than those who consumed legumes once weekly, researchers report in the November 26th issue of the Archives of Internal Medicine. The study was based on interviews and medical exams of more than 9,600 Americans who did not have heart disease when the study began. [Archives of Internal Medicine 2001;161: pp.2573-8].

Legumes contain low levels of sodium and high levels of potassium, calcium and magnesium - a combination that is associated with a reduced risk of heart disease. Folate, a mineral also found in abundance in legumes, is thought to reduce blood levels of homocysteine, a compound that can boost heart disease risk.

Increased dietary copper through legume consumption may protect against heart disease. [Archives of Internal Medicine 162, 15: pp.1780-1, August 12, 2002]

  Increased Fruit/Vegetable Consumption
 A diet high in fruits appears protective against heart disease. The total number of deaths from cardiovascular disease was found to be significantly lower among men with high fruit consumption in one study. A large study of male healthcare professionals found that those men eating mostly a “prudent” diet (high in fruits, vegetables, legumes, whole grains, fish, and poultry) had a 30% lower risk of heart attacks compared to men who ate the fewest foods in the “prudent” category. A parallel study of female healthcare professionals showed a 15% reduction in cardiovascular risk when they ate a diet high in fruits and vegetables compared to the effect of a low fruit and vegetable diet.

  High/Increased Fiber Diet
 A high-fiber diet, particularly one that is high in water-soluble fiber (such as fruit), is associated with decreased risk of both fatal and nonfatal heart attacks, probably because presence of such fiber is known to lower cholesterol. Numerous studies have linked diets rich in fiber with low levels of cholesterol. In particular, soluble fiber alters and lowers fat and cholesterol absorption in the large bowel, helping to reduce LDL, the ‘bad’ cholesterol.

Fiber-rich foods are also good sources of phytochemicals and anti-oxidants that help to lower the risk for heart disease. Blood pressure, a major heart disease risk factor, may also be reduced by eating diet rich in fiber, further helping to reduce the risk of heart disease.

Making positive dietary changes immediately following a heart attack is likely to decrease one’s chance of having a second heart attack. In one study, individuals began eating more vegetables and fruits, and substituted fish, nuts, and legumes for meat and eggs 24 to 48 hours after a heart attack. Six weeks later, the diet group had significantly fewer fatal and nonfatal heart attacks than a similar group that did not make these dietary changes. This trend continued for an additional six weeks.

  Plant-Based Nutrition
 Fruits and vegetables contain antioxidant substances, such as vitamin C, vitamin E, and carotenoids, which protect cells against oxidative damage, which is related to cancer risk and other health problems.[1] The multitude of phytochemicals found in various fruits, vegetables, grains, legumes, and nuts are thought to protect against heart disease and cancer.[2]
  1. Jacob RA, Burri BJ. Oxidative damage and defense. Am J Clin Nutr 1996;63:985S-90S
  2. Craig WJ. Phytochemicals: guardians of our health. J Am Diet Assoc 1997;97:S199-S204

Drug

  Anticoagulant / Blood Thinner

Habits

  Aerobic Exercise
 A sedentary lifestyle of physical inactivity is almost as great a risk factor for heart disease as smoking because of diminished circulation and weight gain.

Research has shown that even moderate exercise can substantially reduce the incidence of coronary events. Aerobic exercise reduces cardiac risk by lowering LDL- and raising HDL-cholesterol levels, and by reducing blood pressure, body fat, blood sugar, mental stress, and blood clotting. Exercise also improves the heart's pumping ability, greatly enhancing the body's functional capacity and stamina.

It is never too late to start. Healthy people who begin exercising after age 45 can reduce their death rate by 23%, and even patients who have already had heart attacks can use medically-supervised aerobic exercise to reduce their risk of another heart attack by up to 25%.

Mineral

  Calcium
 One study showed a 30% to 35% reduction in ischemic heart disease risk in women with a high intake of supplemental calcium. Dietary calcium achieved no significant change in heart attack risk, the researchers noted.

  Chromium
 Getting the right amount of chromium each day may help protect against heart attacks in people that are at high risk, such as those who have diabetes. Chromium seems to improve levels of blood fats such as cholesterol.

Nutrient

  Lycopene
 In Europe, researchers have found a statistically significant association between high dietary lycopene and a 48% lower risk of heart disease. [Am J Epidemiol 1997;146: pp.618-26]

Vitamins

  Folic Acid
 Reduces homocysteine levels (major cause of heart disease), thereby decreasing risk of heart disease. A study found that people with a dietary intake of at least 300mcg per day of folic acid reduced their risk of stroke and heart disease by 20% and 13% respectively, compared with those who consumed less than 136mcg of folic acid per day. [Stroke 2002;33: pp.1183-9]


KEY
Weak or unproven link
Strong or generally accepted link
Proven definite or direct link
Strongly counter-indicative
May do some good
Likely to help
Highly recommended
Reasonably likely to cause problems


GLOSSARY

Adrenaline (Epinephrin, Epinephrine)
A hormone secreted by the adrenal medulla that is released into the bloodstream in response to physical or mental stress, as from fear or injury. It initiates many bodily responses, including the stimulation of heart action and an increase in blood pressure, metabolic rate, and blood glucose concentration.

Aerobic (Aerobically)
Using oxygen. For example, aerobic exercises such as running, swimming, bicycling or playing tennis use up lots of oxygen and burn up lots of calories and fat.

Amino Acid (Amino Acids)
An organic acid containing nitrogen chemical building blocks that aid in the production of protein in the body. Eight of the twenty-two known amino acids are considered "essential," and must be obtained from dietary sources because the body can not synthesize them.

Anti-inflammatory (Antiinflammatory)
Reducing inflammation by acting on body mechanisms, without directly acting on the cause of inflammation, e.g., glucocorticoids, aspirin.

Antioxidant (Antioxidants)
A chemical compound that slows or prevents oxygen from reacting with other compounds. Some antioxidants have been shown to have cancer-protecting potential because they neutralize free radicals. Examples include vitamins C and E, beta carotene, the minerals selenium and germanium, superoxide dismutase (SOD), coenzyme Q10, catalase, and some amino acids.

Apnea
Cessation of breathing.

Arrhythmia (Arrhythmias)
A condition caused by variation in the regular rhythm of the heartbeat. Arrhythmias may cause serious conditions such as shock and congestive heart failure, or even death.

Arterial (Arteries, Artery)
Blood that leaves the heart. When it leaves the right ventricle, it is venous blood; and when it leaves the left ventricle, through the aorta, it is fresh and oxygenated. After it has passed out to the capillaries and started to return, it is venous blood.

Arteriosclerosis
A common arterial disorder. Characterized by calcified yellowish plaques, lipids, and cellular debris in the inner layers of the walls of large and medium-sized arteries.

Ascorbate
A mineral salt of ascorbic acid (i.e., vitamin C) that aids in the absorption of both vitamin C and the mineral.

Atherosclerosis
Common form of arteriosclerosis associated with the formation of atheromas which are deposits of yellow plaques containing cholesterol, lipids, and lipophages within the intima and inner media of arteries. This results in a narrowing of the arteries, which reduces the blood and oxygen flow to the heart and brain as well as to other parts of the body and can lead to a heart attack, stroke, or loss of function or gangrene of other tissues.

BID
Twice per day.

Biopsy
Removal of a sample of tissue from a living being for diagnosis. A pathologist later uses a microscope to look for certain features, such as cancer cells, in the sample. A fine-needle aspiration biopsy involves inserting a thin needle to remove a small amount of tissue, sometimes using CT or ultrasound to guide the needle. A core biopsy involves obtaining a sample of tissue with a thick needle or by inserting a thin, lighted tube (laparoscope) into a small incision in the abdomen. Another biopsy method is to remove tissue during an operation.

Calcium
The body's most abundant mineral. Its primary function is to help build and maintain bones and teeth. The body also needs calcium to carry nerve signals, keep the heart functioning, contract muscles, clot blood and maintain healthy skin. Calcium helps control blood acid-alkaline balance, plays a role in cell division, muscle growth and iron utilization, activates certain enzymes, and helps transport nutrients through cell membranes. Calcium also forms a cellular cement called ground substance that helps hold cells and tissues together.

Cancer
Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.

Carbohydrates (Carbohydrate)
The sugars and starches in food. Sugars are called simple carbohydrates and found in such foods as fruit and table sugar. Complex carbohydrates are composed of large numbers of sugar molecules joined together, and are found in grains, legumes, and vegetables like potatoes, squash, and corn.

Cardiac
Pertaining to the heart, also, pertaining to the stomach area adjacent to the esophagus.

Cardiovascular
Pertaining to the heart and blood vessels.

Chlamydia
A sexually-transmitted disease that is often without symptoms. Some females experience a white vaginal discharge that resembles cottage cheese, a burning sensation when urinating, itching, and painful intercourse. A clear watery urethral discharge in the male probably is a chlamydia infection.

Cholesterol
A waxy, fat-like substance manufactured in the liver and found in all tissues, it facilitates the transport and absorption of fatty acids. In foods, only animal products contain cholesterol. An excess of cholesterol in the bloodstream can contribute to the development of atherosclerosis.

Chromium
Chromium is a mineral that becomes a part of the glucose tolerance factor (GTF). Chromium aids in insulin utilization and blood sugar control. By controlling blood sugar, chromium helps prevent the damage caused by glucose, which is called glycation. Chromium helps maintain normal cholesterol levels and improves high-density lipoprotein levels. Chromium is also important in building muscle and reducing obesity.

Chronic (Chronicity)
Usually referring to chronic illness: Illness extending over a long period of time.

Cobalamin (B12, B-12, Cobalamine, Vitamin B12)
Essential for normal growth and functioning of all body cells, especially those of bone marrow (red blood cell formation), gastrointestinal tract and nervous system, it prevents pernicious anemia and plays a crucial part in the reproduction of every cell of the body i.e. synthesis of genetic material (DNA).

Copper
An essential mineral that is a component of several important enzymes in the body and is essential to good health. Copper is found in all body tissues. Copper deficiency leads to a variety of abnormalities, including anemia, skeletal defects, degeneration of the nervous system, reproductive failure, pronounced cardiovascular lesions, elevated blood cholesterol, impaired immunity and defects in the pigmentation and structure of hair. Copper is involved in iron incorporation into hemoglobin. It is also involved with vitamin C in the formation of collagen and the proper functioning in central nervous system. More than a dozen enzymes have been found to contain copper. The best studied are superoxide dismutase (SOD), cytochrome C oxidase, catalase, dopamine hydroxylase, uricase, tryptophan dioxygenase, lecithinase and other monoamine and diamine oxidases.

CVD
Cardiovascular Disease.

Cysteine
A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. Cysteine is a sulfur-bearing amino acid with antioxidant properties. It is important for keratin synthesis, a protein found in skin, hair and nails and is a component of coenzyme A and glutathione.

Cytomegalovirus (CMV)
A member of the herpes virus family which may induce the immune-deficient state or cause active illness, such as pneumonia, in a patient already immune-deficient due to chronic illness, such as cancer or organ transplantation therapy.

DHA
Docosahexanoic Acid. A metabolite of the omega-3 fatty acid alpha-linolenic acid.

DHEA (DHEA-S)
Dehydroepiandrosterone (DHEA) is a steroid produced by the adrenal glands and is the most abundant one found in humans. DHEA may be transformed into testosterone, estrogen or other steroids. It is found in the body as DHEA or in the sulfated form known as DHEA-S. One form is converted into the other as needed.

Diabetes Mellitus (Diabetes, Diabetic, Diabetics)
A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.

Diastolic
Pertaining to the relaxation phase of the heartbeat, or period when the heart muscle is resting and filling with blood. When used in blood pressure readings (for example 120/80), it refers to the second/lower number.

Dietary Fiber (Insoluble Fiber, Insoluble Fibers, Soluble Fiber, Soluble Fibers)
There are two types of dietary fiber - soluble and insoluble. Insoluble fiber acts like a sponge; it absorbs water and moves solid waste out of the intestines. It is found mainly in whole grains and on the outside of seeds, fruits, and legumes. Soluble fiber is found in fruits, vegetables, seeds, brown rice, barley, oats and oat bran. It forms a gel when mixed with liquid producing a softer stool. It also prevents and reduces the absorption of certain substances from the intestines into the bloodstream.

Dilatation
Normal increase in the size of a body opening, blood vessel, or tube.

EPA
Environmental Protection Agency. Also: Eicosapentanoic Acid. A metabolite of the omega-3 fatty acid alpha-linolenic acid.

Epidemiology
The study of the causes and distribution of disease in human populations.

Fatty Acids (Fatty Acid)
Chemical chains of carbon, hydrogen, and oxygen atoms that are part of a fat (lipid) and are the major component of triglycerides. Depending on the number and arrangement of these atoms, fatty acids are classified as either saturated, polyunsaturated, or monounsaturated. They are nutritional substances found in nature which include cholesterol, prostaglandins, and stearic, palmitic, linoleic, linolenic, eicosapentanoic (EPA), and decohexanoic acids. Important nutritional lipids include lecithin, choline, gamma-linoleic acid, and inositol.

Folic Acid
A B-complex vitamin that functions along with vitamin B-12 and vitamin C in the utilization of proteins. It has an essential role in the formation of heme (the iron containing protein in hemoglobin necessary for the formation of red blood cells) and DNA. Folic acid is essential during pregnancy to prevent neural tubular defects in the developing fetus.

Free Radical (Free Radicals)
A free radical is an atom or group of atoms that has at least one unpaired electron. Because another element can easily pick up this free electron and cause a chemical reaction, these free radicals can effect dramatic and destructive changes in the body. Free radicals are activated in heated and rancid oils and by radiation in the atmosphere, among other things.

Gout
A disease characterized by an increased blood uric acid level and sudden onset of episodes of acute arthritis.

Gram (gm, gms, Gramme, Grammes, Grams)
A metric unit of weight, there being approximately 28 grams in one ounce.

Helicobacter Pylori (Pylori)
H. pylori is a bacterium that is found in the stomach which, along with acid secretion, damages stomach and duodenal tissue, causing inflammation and peptic ulcers. Although most people will never have symptoms or problems related to the infection, they may include: dull, 'gnawing' pain which may occur 2-3 hours after a meal, come and go for several days or weeks, occur in the middle of the night when the stomach is empty and be relieved by eating; loss of weight; loss of appetite; bloating; burping; nausea; vomiting.

Hemochromatosis
A rare disease in which iron deposits build up throughout the body. Enlarged liver, skin discoloration, diabetes mellitus, and heart failure may occur.

Herpes
A small group of capsid-forming DNA viruses, sometimes divided into Type I (forming vesicles and blisters on the mouth, lips-generally above the waist) and Type II (usually sexually-transmitted, with symptoms mostly below the waist). Both types form acute initial outbreaks, go dormant, reactivate, and so forth. For most folks, frequent outbreaks are clear signs of stress or immunosuppression. Both types are equally dangerous for infants.

High-Density Lipoprotein (HDL)
Also known as "good" cholesterol, HDLs are large, dense, protein-fat particles that circulate in the blood picking up already used and unused cholesterol and taking them back to the liver as part of a recycling process. Higher levels of HDLs are associated with a lower risk of cardiovascular disease because the cholesterol is cleared more readily from the blood.

Hydrochloric Acid (HCl)
An inorganic acidic compound, excreted by the stomach, that aids in digestion.

Hydrogenated Fat (Hydrogenated Fats, Hydrogenated Oil, Hydrogenated Oils)
Usually containing trans-fatty acids (or simply "trans" fats), hydrogenated fats show up mostly in margarine, shortening and many prepared and processed foods such as cookies, crackers, cakes, potato chips and other deep-fried foods. The best way to spot hydrogenated fats is to read the ingredient lists on foods and identify those listing hydrogenated or "partially" hydrogenated fats.

Hypertension
High blood pressure. Hypertension increases the risk of heart attack, stroke, and kidney failure because it adds to the workload of the heart, causing it to enlarge and, over time, to weaken; in addition, it may damage the walls of the arteries.

Insulin
A hormone secreted by the pancreas in response to elevated blood glucose levels. Insulin stimulates the liver, muscles, and fat cells to remove glucose from the blood for use or storage.

Iron
An essential mineral. Prevents anemia: as a constituent of hemoglobin, transports oxygen throughout the body. Virtually all of the oxygen used by cells in the life process are brought to the cells by the hemoglobin of red blood cells. Iron is a small but most vital, component of the hemoglobin in 20,000 billion red blood cells, of which 115 million are formed every minute. Heme iron (from meat) is absorbed 10 times more readily than the ferrous or ferric form.

Ischemia (Ischemic)
Localized tissue anemia due to obstruction of the inflow of arterial blood. A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels.

IU (mIU, uIU)
International Unit: An arbitrarily defined but agreed upon unit that depends on what is being measured.
mIU: 0.001 or one thousandth of an IU.
uIU: 0.000001 or one millionth of an IU.

Lesion (Lesions)
Any damage to tissue structure or function; an abnormal change in body tissue caused by disease or injury. A scar is a lesion, as is cancer, a stomach ulcer or a pimple.

Lipoproteins (Lipoprotein)
Molecules composed of lipids and proteins that carry fats and cholesterol through the bloodstream.

Low-Density Lipoprotein (LDL)
Also known as "bad" cholesterol, LDLs are large, dense, protein-fat particles composed of a moderate proportion of protein and a high proportion of cholesterol. Higher levels of LDLs are associated with a greater risk of cardiovascular disease.

Lung (Lungs, Pulmonary)
Organ of the body, located in the chest cavity which is designed to bring oxygen from the air into the blood stream, while also expelling carbon dioxide and other waste gases out of the body. Pulmonary: Related to the lungs.

Lysine
Essential amino acid. Important for growth, tissue repair, and the production of hormones, enzymes and antibodies. Research indicates that lysine may be useful in the treatment of migraine and herpes simplex. Precursor to carnitine in the body.

Magnesium
An essential mineral. The chief function of magnesium is to activate certain enzymes, especially those related to carbohydrate metabolism. Another role is to maintain the electrical potential across nerve and muscle membranes. It is essential for proper heartbeat and nerve transmission. Magnesium controls many cellular functions. It is involved in protein formation, DNA production and function and in the storage and release of energy in ATP. Magnesium is closely related to calcium and phosphorus in body function. The average adult body contains approximately one ounce of magnesium. It is the fifth mineral in abundance within the body--behind calcium, phosphorus, potassium and sodium. Although about 70 percent of the body's magnesium is contained in the teeth and bones, its most important functions are carried out by the remainder which is present in the cells of the soft tissues and in the fluid surrounding those cells.

Malabsorption
Improper utilization of needed and available nutrients, either from impaired digestive function (such as B12 being unabsorbed because of gastritis), impaired absorption (poor Vitamin E absorption because of an inflamed ileum) or impaired transport (the diminished blood proteins of the advanced alcoholic). There are other causes as well.

Microgram (mcg, Micrograms, ug)
0.000001 or a millionth of a gram.

Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.

Mineral (Minerals)
Plays a vital role in regulating many body functions. They act as catalysts in nerve response, muscle contraction and the metabolism of nutrients in foods. They regulate electrolyte balance and hormonal production, and they strengthen skeletal structures.

Phytochemicals (Phytochemical)
Substances such as vitamins and minerals that occur naturally in plants and have been shown in research to possibly prevent or cure disease.

Polyunsaturated
Polyunsaturated fats or oils. Originate from vegetables and are liquid at room temperature. These oils are a good source of the unsaturated fatty acids. They include flaxseed with added vitamin B6 (pyridoxine), sunflower oil, safflower oil, and primrose oil.

Postprandial
Following a meal.

Potassium
A mineral that serves as an electrolyte and is involved in the balance of fluid within the body. Our bodies contain more than twice as much potassium as sodium (typically 9oz versus 4oz). About 98% of total body potassium is inside our cells. Potassium is the principal cation (positive ion) of the fluid within cells and is important in controlling the activity of the heart, muscles, nervous system and just about every cell in the body. Potassium regulates the water balance and acid-base balance in the blood and tissues. Evidence is showing that potassium is also involved in bone calcification. Potassium is a cofactor in many reactions, especially those involving energy production and muscle building.

Prostate
The prostate gland in men that surrounds the neck of the bladder and the urethra and produces a secretion that liquefies coagulated semen.

Saturated Fat (Saturated Fats)
A type of fat that is readily converted to LDL cholesterol and is thought to encourage production of arterial disease. Saturated fats tend to be hard at room temperature. Among saturated fats are animal fats, dairy products, and such vegetable oils as coconut and palm oils.

Selenium
An essential element involved primarily in enzymes that are antioxidants. Three selenium- containing enzymes are antioxidant peroxidases and a fourth selenium-containing enzyme is involved in thyroid hormone production. The prostate contains a selenium-containing protein and semen contains relatively large amounts of selenium. Clinical studies show that selenium is important in lowering the risk of several types of cancers. In combination with Vitamin E, selenium aids the production of antibodies and helps maintain a healthy heart. It also aids in the function of the pancreas, provides elasticity to tissues and helps cells defend themselves against damage from oxidation.

Serum
The cell-free fluid of the bloodstream. It appears in a test tube after the blood clots and is often used in expressions relating to the levels of certain compounds in the blood stream.

Sodium
An essential mineral that our bodies regulate and conserve. Excess sodium retention increases the fluid volume (edema) and low sodium leads to less fluid and relative dehydration. The adult body averages a total content of over 100 grams of sodium, of which a surprising one-third is in bone. A small amount of sodium does get into cell interiors, but this represents only about ten percent of the body content. The remaining 57 percent or so of the body sodium content is in the fluid immediately surrounding the cells, where it is the major cation (positive ion). The role of sodium in the extracellular fluid is maintaining osmotic equilibrium (the proper difference in ions dissolved in the fluids inside and outside the cell) and extracellular fluid volume. Sodium is also involved in nerve impulse transmission, muscle tone and nutrient transport. All of these functions are interrelated with potassium.

Spasm
Involuntary contraction of one or more muscle groups.

Statins (Statin)
A class of drugs that lower cholesterol.

Stroke (Stroke-Type Event)
A sudden loss of brain function caused by a blockage or rupture of a blood vessel that supplies the brain, characterized by loss of muscular control, complete or partial loss of sensation or consciousness, dizziness, slurred speech, or other symptoms that vary with the extent and severity of the damage to the brain. The most common manifestation is some degree of paralysis, but small strokes may occur without symptoms. Usually caused by arteriosclerosis, it often results in brain damage.

Synergistic
Having the property that the total combined effect of two or more factors exceeds the sum of their individual effects.

Systolic
Pertaining to the contraction phase of the heartbeat, or the pressure in the arterial system caused by the heart as blood is being pumped out. When used in blood pressure readings (for example 120/80), it refers to the first/upper number.

Testosterone
The principal male sex hormone that induces and maintains the changes that take place in males at puberty. In men, the testicles continue to produce testosterone throughout life, though there is some decline with age. A naturally occurring androgenic hormone.

Triglyceride (Triglycerides)
The main form of fat found in foods and the human body. Containing three fatty acids and one unit of glycerol, triglycerides are stored in adipose cells in the body, which, when broken down, release fatty acids into the blood. Triglycerides are fat storage molecules and are the major lipid component of the diet.

Uric Acid (Hyperuricemia)
The final end product of certain native or dietary proteins, especially the nucleoproteins found in the nucleus of cells. Unlike the much smaller nitrogenous waste product urea, which is mostly recycled to form many amino acids, uric acid is an unrecycleable metabolite that must be excreted: nucleoprotein to purine to uric acid to the outside in the urine or the sweat. Hyperuricemia: Having elevated blood uric acid, either from a rapid rate of cell breakdown and synthesis (such as might occur from fasting, heavy training, trauma or any number of major diseases), a high consumption of organ meats, glandular supplements or spirulina, or the inability (usually hereditary) to excrete uric acid in the urine as fast as it is produced, even though production itself is not elevated.

Vascular
Relating to the blood vessels of the body. The blood vessels of the body, as a group, are referred to as the vascular system. They are composed of arteries, veins and capillaries - arteries that pass oxygen-rich blood to the tissues of the body; veins which return oxygen-depleted blood from the tissues to the lungs for oxygen; and the capillaries that are the tiniest vessels and are between the arteries and veins.

Vegetarian (Lacto-Ovo-Vegetarian, Vegetarianism, Vegetarians)
A person who consumes no meat, fish or fowl (chicken, turkey, etc.), but who may consume animal products such as dairy products (milk, cheese, butter, etc.), eggs or honey.

Virus (Viri, Viruses)
Any of a vast group of minute structures composed of a protein coat and a core of DNA and/or RNA that reproduces in the cells of the infected host. Capable of infecting all animals and plants, causing devastating disease in immunocompromised individuals. Viruses are not affected by antibiotics, and are completely dependent upon the cells of the infected host for the ability to reproduce.

Vitamin B6 (B6, B-6)
Influences many body functions including regulating blood glucose levels, manufacturing hemoglobin and aiding the utilization of protein, carbohydrates and fats. It also aids in the function of the nervous system.

Vitamin C (Ascorbic Acid)
A water-soluble antioxidant vitamin essential to the body's health. When bound to other nutrients, for example calcium, it would be referred to as "calcium ascorbate". As an antioxidant, it inhibits the formation of nitrosamines (a suspected carcinogen). Vitamin C is important for maintenance of bones, teeth, collagen and blood vessels (capillaries), enhances iron absorption and red blood cell formation, helps in the utilization of carbohydrates and synthesis of fats and proteins, aids in fighting bacterial infections, and interacts with other nutrients. It is present in citrus fruits, tomatoes, berries, potatoes and fresh, green leafy vegetables.

Vitamin E
An essential fat-soluble vitamin. As an antioxidant, helps protect cell membranes, lipoproteins, fats and vitamin A from destructive oxidation. It helps protect red blood cells and is important for the proper function of nerves and muscles. For Vitamin E only, 1mg translates to 1 IU.

Vitamin K
Helps the blood clot when the body is injured.

X-rays (X-ray)
High-energy radiation used to take pictures of areas inside the body.




Last updated: May 04, 2008


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