Signs, symptoms & indicators of Elevated Insulin Levels: |  |  |  | | Lab Values - Common | High systolic blood pressure
High diastolic blood pressure | Symptoms - Hair |
Early male pattern baldness | Although early baldness on the top of the head may be a non-modifiable risk factor for heart disease, it may serve as a useful clinical marker to identify men at increased risk of insulin problems and cardiac risk who would benefit from more detailed screening and lifestyle, dietary, nutritional and other interventive therapies. [Lancet September 30, 2000; 356: pp.1165-1166] |
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Conditions that suggest Elevated Insulin Levels:
Risk factors for Elevated Insulin Levels: |  |  |  | | Childhood | Early puberty onset | Girls with premature puberty have been found to have elevated insulin and DHEA-S levels. This contributes to the weight gain usually seen in advanced PCOS." |
| Habits |
Lack of Sleep | A study found that people who do not get enough sleep on a regular basis may become less sensitive to insulin which, over time, can raise the risk of obesity, high blood pressure and diabetes. Chronic sleep deprivation (under 6.5 hours per night) had the same effect on insulin resistance as aging. |
| Mental |
Stress | One of cortisol's undesirable effects is that it contributes to insulin resistance by decreasing the rate of glucose uptake, probably by blocking the insulin receptor. [J Clin endocrinol Metab 54 (1982): pp.131-8] |
| Symptoms - Metabolic |
Apple-shaped body when overweight |
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Elevated Insulin Levels suggests the following may be present: |  |  |  | | Habits | Lack of Sleep | A study found that people who do not get enough sleep on a regular basis may become less sensitive to insulin which, over time, can raise the risk of obesity, high blood pressure and diabetes. Chronic sleep deprivation (under 6.5 hours per night) had the same effect on insulin resistance as aging. |
| Mental |
Stress | One of cortisol's undesirable effects is that it contributes to insulin resistance by decreasing the rate of glucose uptake, probably by blocking the insulin receptor. [J Clin endocrinol Metab 54 (1982): pp.131-8] |
| Metabolic |
Syndrome X | Uro-Genital |
Polycystic Ovary Syndrome (PCOS) | Researchers found that 75% of women studied with PCOS were hyperinsulinemic. [Fertil Steril 2000;73(1): pp.150-156, J Clin Endocrinol Metab 1999;84(6): pp.1897-1899] |
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Elevated Insulin Levels can lead to:
Recommendations and treatments for Elevated Insulin Levels: |  |  |  | | Botanical | Cinnamon | Cinnamon with each meal helps keep insulin and blood sugar levels under control. The typical 1/2 to 3/4 teaspoon dose contains a phytochemical called methyl hydroxy chalcone polymer (MHCP) which improves cellular glucose utilization and increases the sensitivity of insulin receptors in laboratory studies. Personal testimonies indicate that this effect is seen in humans, but further study is required to confirm this. |
| Diet |
Sugars Avoidance / Reduction
Weight Loss
Milk/Dairy Products | A higher consumption of dairy products was associated with a reduced risk of insulin resistance (Syndrome X) in a study of 3,157 young adults followed for a 10 year period. [JAMA 2002;287(16): pp.2081-9] |
| Extract |
DIM (di-indolmethane)/I3C (Indole-3-Carbinol) | DIM has been reported to enhance insulin sensitivity and encourage abdominal fat loss. |
| Habits |
Aerobic Exercise | Mineral |
Chromium | Chromium picolinate supplementation at 1,000mcg per day over a 13-week period combined with exercise decreased total cholesterol, LDL cholesterol and insulin levels in a recent small study of both males and females. [J Nutr Biochem, 1998;9: pp.471-5] |
| Nutrient |
DHA (docosahexaenoic acid) | DHA at 1.8gm per day improved insulin sensitivity while having no effect on insulin secretion, in a pilot study of 12 overweight adults 45-70 years old. [Experimental Biology, April 20-24, 2002, New Orleans, Louisiana, USA; abstract] |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Proven definite or direct link |  |  | May do some good |  |  | Likely to help |  |  | Highly recommended |
GLOSSARY
Abdomen (Abdominal) That part of the body between the chest and the hips that contains the stomach, intestines, liver, bladder, pancreas and other organs.
Carbohydrates (Carbohydrate) The sugars and starches in food. Sugars are called simple carbohydrates and found in such foods as fruit and table sugar. Complex carbohydrates are composed of large numbers of sugar molecules joined together, and are found in grains, legumes, and vegetables like potatoes, squash, and corn.
Cardiac Pertaining to the heart, also, pertaining to the stomach area adjacent to the esophagus.
Cholesterol A waxy, fat-like substance manufactured in the liver and found in all tissues, it facilitates the transport and absorption of fatty acids. In foods, only animal products contain cholesterol. An excess of cholesterol in the bloodstream can contribute to the development of atherosclerosis.
Chromium Chromium is a mineral that becomes a part of the glucose tolerance factor (GTF). Chromium aids in insulin utilization and blood sugar control. By controlling blood sugar, chromium helps prevent the damage caused by glucose, which is called glycation. Chromium helps maintain normal cholesterol levels and improves high-density lipoprotein levels. Chromium is also important in building muscle and reducing obesity.
Chronic (Chronicity) Usually referring to chronic illness: Illness extending over a long period of time.
DHA Docosahexanoic Acid. A metabolite of the omega-3 fatty acid alpha-linolenic acid.
DHEA (DHEA-S) Dehydroepiandrosterone (DHEA) is a steroid produced by the adrenal glands and is the most abundant one found in humans. DHEA may be transformed into testosterone, estrogen or other steroids. It is found in the body as DHEA or in the sulfated form known as DHEA-S. One form is converted into the other as needed.
Diabetes Mellitus (Diabetes, Diabetic, Diabetics) A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.
Glucose A sugar that is the simplest form of carbohydrate. It is commonly referred to as blood sugar. The body breaks down carbohydrates in foods into glucose, which serves as the primary fuel for the muscles and the brain.
Gout A disease characterized by an increased blood uric acid level and sudden onset of episodes of acute arthritis.
Gram (gm, gms, Gramme, Grammes, Grams) A metric unit of weight, there being approximately 28 grams in one ounce.
Hyperlipidemia Increased cholesterol level: Elevated blood fats, either from heredity, from having so many calories in the diet that they are ending up as liver-synthesized storage fats, from an excessively anabolic metabolism. Also from a constellation of less common disease causes.
Hypertension High blood pressure. Hypertension increases the risk of heart attack, stroke, and kidney failure because it adds to the workload of the heart, causing it to enlarge and, over time, to weaken; in addition, it may damage the walls of the arteries.
Hypoglycemia A condition characterized by an abnormally low blood glucose level. Severe hypoglycemia is rare and dangerous. It can be caused by medications such as insulin (diabetics are prone to hypoglycemia), severe physical exhaustion, and some illnesses.
Insulin A hormone secreted by the pancreas in response to elevated blood glucose levels. Insulin stimulates the liver, muscles, and fat cells to remove glucose from the blood for use or storage.
Low-Density Lipoprotein (LDL) Also known as "bad" cholesterol, LDLs are large, dense, protein-fat particles composed of a moderate proportion of protein and a high proportion of cholesterol. Higher levels of LDLs are associated with a greater risk of cardiovascular disease.
Microgram (mcg, Micrograms, ug) 0.000001 or a millionth of a gram.
Phytochemicals (Phytochemical) Substances such as vitamins and minerals that occur naturally in plants and have been shown in research to possibly prevent or cure disease.
Syndrome A medical condition characterized by a collection of related symptoms (what the patient feels) and signs (what a doctor can observe or measure).
Teaspoon (Teaspoons, tsp) Equivalent to 5cc (5ml).
Last updated: Apr 13, 2008
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