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Enteritis
  Enteritis
 Treatment recommendations
 


Enteritis means inflammation of the intestinal tract, especially of the small intestine. Serious complications may occur, especially in infants and the elderly. Types of enteritis include:

Enterocolitis involves the colon as well as the small intestine, and gastroenteritis includes stomach inflammation. Regional enteritis (ileitis, or Crohn disease) is a chronic inflammation that, in its common form, is confined to the terminal portion of the ileum.

Causes & Development
Enteritis may be caused by irritants, poisons, viral or bacterial infections, or other unknown factors.

Signs & Symptoms
Symptoms are extremely variable but usually include continuous or intermittent diarrhea, which may be bloody, painful abdominal cramps. Fever is also common.

Diagnosis & Tests
The following laboratory tests are useful in diagnosing Campylobacter Enteritis; Antibiotic-Associated Pseudomembranous Colitis; Shigellosis; Nontyphoidal Salmonellosis; Enterocolitis; Paratyphoid fever; Bacteremia:Treatment & Prevention
Treatment for all forms of enteritis is generally focused on relief of symptoms, with anti-inflammatory agents playing an important role.

Complications
Liver involvement (diagnosed through increased serum LDH (especially LDH), alkaline phosphatase, SGOT (AST); Intestinal ulceration (blood in stool during second to third week); Relapse (positive blood culture).





Recommendations and treatments for Enteritis:
Lab Tests/Rule-Outs  Stool Exam


KEY
Highly recommended


GLOSSARY

Abdomen (Abdominal)
That part of the body between the chest and the hips that contains the stomach, intestines, liver, bladder, pancreas and other organs.

Alkaline
A substance having a pH above that of neutral water (7.0) when in solution. Signified as pH (potential of Hydrogen), alkaline fluids, such as the blood (pH about 7.4), have the ability to neutralize acids (solutions below pH 7.0). Metabolic wastes are acids, and the alkaline reserve of the blood neutralizes them until they are excreted.

Anti-inflammatory (Antiinflammatory)
Reducing inflammation by acting on body mechanisms, without directly acting on the cause of inflammation, e.g., glucocorticoids, aspirin.

Bacteria (Bacterial, Bacterium)
Microscopic germs. Some bacteria are "harmful" and can cause disease, while other "friendly" bacteria protect the body from harmful invading organisms.

Chronic (Chronicity)
Usually referring to chronic illness: Illness extending over a long period of time.

Colitis
Colon inflammation, usually involving the mucus membranes. Mucus colitis is a type with cramps, periods of constipation, and copious discharge of mucus with feces. Ulcerative colitis has pain, inflammation, ulceration, fever, and bleeding, all interspersed at various times - a long and serious illness.

Colon (Colonic)
The part of the large intestine that extends to the rectum. The colon takes the contents of the small intestine, moving them to the rectum by contracting.

Cramp (Cramping, Cramps)
A sudden, involuntary, painful muscular contraction.

Crohn's Disease (Crohn's)
Chronic inflammatory disease of the gastrointestinal tract. The most common symptoms are abdominal pain, often in the lower right area, and diarrhea. Rectal bleeding, weight loss, and fever may also occur. Bleeding may be serious and persistent, leading to anemia.

Diarrhea
Excessive discharge of contents of bowel.

Enteritis
Sometimes Enteritis regionalis: Localized inflammation of the intestine.

Gastroenteritis
Gastrointestinal tract inflammation; characterized by abdominal pain, nausea, diarrhea, vomiting; which may be caused by bacteria, parasites or a virus.

Ileum
The lower two-thirds of the small intestine, ending in the ileocecal valve and emptying into the cecum of the colon. The last foot of the ileum is the only absorption site available for important dietary substances such as vitamin B12, folic acid, some essential fatty acids, fat soluble vitamins, and recycled bile acids.

Leukocyte (Leukocytes)
A white blood cell which appears 5,000 to 10,000 times in each cubic millimeter of normal human blood. Among the most important functions are destroying bacteria, fungi and viruses and rendering harmless poisonous substances that may result from allergic reactions and cell injury.

Liver (Hepatic)
The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.

Macrophage (Macrophages)
An immune system cell that scavenges bacterial and other foreign material in the blood and tissues. It is a mature form of what is released from the marrow as a monocyte. A macrophage lives long, can digest much detritus, and is able to wear particles of odd food on its outer membrane. This allows T-cell and B-cell lymphocytes to taste the particle (an epitope) and form an antibody response. Further, these macrophages, traveling as monocytes, will take up permanent residence in many tissues, providing them with immunity. They line the spleen, form the cleansing Kupffer cells in the liver, make up the "dust cells" that protect the lungs, protect the synovial fluids of the joints, and form the microglial cells that provide protection to the brain and nerve tissues. Essentially the macrophages clean up messes and act as the intermediates between innate and acquired immunity.

Mucus (Mucous)
The viscous, slippery substance that consists chiefly of mucin, water, cells, and inorganic salts and is secreted as a protective lubricant coating by cells and glands of the mucous membranes.

Occult Blood
Usually detected through an occult blood test: A test used in screening for blood found in the stool, sputum or urine. The most common test is for hidden blood in the stool, also known as a stool guaiac or hemoccult test, which usually indicates the presence of ulceration or cancer.

Salmonella
A widespread genus of gram-negative motile-rod bacteria, some of which can cause moderate GI infections, while several can produce metabolites in food that cause serious toxic reaction when the food is eaten.

Serum
The cell-free fluid of the bloodstream. It appears in a test tube after the blood clots and is often used in expressions relating to the levels of certain compounds in the blood stream.

SGOT (SGPT)
SGOT and SGPT: Liver enzymes that are normally only present in minute quantities in the blood, but become elevated under a variety of circumstances, particularly hepatitis.

Small Intestine (Small Bowel)
The small intestine lies between the stomach and the large intestine. It is about 6 meters (20 feet) long and its primary function is to digest (break down) food and absorb nutrients (vitamins, minerals, proteins, carbohydrates, and fats). The small intestine makes up more than 70% of the length and 90% of the surface area of the gastrointestinal (GI) tract.

Staphylococcus (Staph, Staphylococcal)
A genus of micrococci bacteria with many members that can cause disease. They are gram-positive, nonmotile bacteria
that are aerobic-(unless they need to be anaerobic). Staph of various types are responsible for boils and carbuncles; they may be involved in impetigo, toxic shock syndrome, endocarditis, osteomyelitis, and urinary tract infections, as well as some food poisoning. They stay around hospitals and veterinary clinics waiting to get you. They are also a normal part of the mouth, throat, and skin flora in a third to a half of all of us, causing no problems, but just waiting. Staph has always been with us. Some even eat our antibiotics for breakfast.

Stomach
A hollow, muscular, J-shaped pouch located in the upper part of the abdomen to the left of the midline. The upper end (fundus) is large and dome-shaped; the area just below the fundus is called the body of the stomach. The fundus and the body are often referred to as the cardiac portion of the stomach. The lower (pyloric) portion curves downward and to the right and includes the antrum and the pylorus. The function of the stomach is to begin digestion by physically breaking down food received from the esophagus. The tissues of the stomach wall are composed of three types of muscle fibers: circular, longitudinal and oblique. These fibers create structural elasticity and contractibility, both of which are needed for digestion. The stomach mucosa contains cells which secrete hydrochloric acid and this in turn activates the other gastric enzymes pepsin and rennin. To protect itself from being destroyed by its own enzymes, the stomach’s mucous lining must constantly regenerate itself.

Ulcer (Ulceration, Ulcers)
Lesion on the skin or mucous membrane.




Last updated: Jun 22, 2008


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