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Low Total Cholesterol
  Cholesterol, Low Total
 Conditions that suggest it
 Contributing risk factors
 Treatment recommendations
 


Doctors have long warned about the health hazards of high cholesterol but a growing body of evidence indicates that very low cholesterol can be dangerous too. Low cholesterol levels have been associated with depression, anxiety, violent behavior, suicide and hemorrhagic stroke. Treatment & Prevention


Fat absorption requires the presence of bile as an emulsifier. Both a very low fat diet and poor bile flow can work to keep cholesterol levels lower than they should be. Thinning the bile can help raise low cholesterol levels.

Complications
A study of 121 healthy young women found that those with low cholesterol levels - below 160mg/dl - were more likely to score high on measures of depression and anxiety than women with normal or high cholesterol levels. Normal cholesterol levels are considered to fall within the range of 180mg/dl to 200mg/dl. There is now a compelling body of evidence in both men and women that low cholesterol is a potential predictor for depression and anxiety in certain individuals. [Psychosomatic Medicine, May 1999]

Data from more than 300 peer-reviewed medical reports showed that men with blood cholesterol levels below 160mg/dl tended to be the victims of homicide, suicide or fatal accidents 50-80% more often than those with the highest levels of cholesterol. The statistics for women showed a similar increase of 30%. The author of the review said that there may be a possible link between low cholesterol and a reduction in the brain chemical serotonin. Individuals with low serotonin levels are known to be more likely to commit suicide, especially by violent means, as well as homicide.





Conditions that suggest Low Total Cholesterol:
Circulation  Stroke
 Researchers have found that as cholesterol levels drop, the risk of hemorrhagic stroke (accounting for 20% of strokes) increased significantly. A person with a cholesterol level below 180mg/dl had twice the risk of that type of stroke when compared with someone at a level of 230mg/dl.

Hormones

  Low Pregnenolone Level
  Progesterone Low or Estrogen Dominance
 Cholesterol is the raw material used to make progesterone, and is therefore its immediate precursor.

  Low DHEA Level
  Estrogens Low

Risk factors for Low Total Cholesterol:
Lab Values - Chemistries  Low total cholesterol level (confirmed)

Recommendations and treatments for Low Total Cholesterol:
Amino Acid / Protein  L-Taurine
 Taurine and beet concentrate are very effective at thinning the bile in the gallbladder.

Detoxification

  Liver/Gall Bladder Flush
 The liver/gallbladder flush helps to remove thickened bile by mobilizing it.

Diet

  Coconut
  Increased Fruit/Vegetable Consumption
  Beetroot

Lab Tests/Rule-Outs

  Test for Hormones
 A chronically low serum cholesterol level can be an unsuspected problem. Since cholesterol is the precursor to the adrenal and sex steroids, low levels may mean an insufficient supply of raw material for hormone production. When there are indications of hormone insufficiency, appropriate lab testing should be conducted.


KEY
Weak or unproven link
Strong or generally accepted link
Proven definite or direct link
May do some good
Likely to help


GLOSSARY

Adrenal (Adrenal Gland, Adrenal Glands, Adrenals)
The adrenal glands sit on top of each kidney and consist of an outer cortex and an inner medulla. Of the 50 or so hormones the adrenals make, only cortisone and adrenaline are recognized by most people. Some of these hormones must be produced to preserve life, while others help resist stress. Other hormones from the adrenals control normal energy output (along with the thyroid) and govern the breakdown of stored energy into quick energy sources. The medulla produces epinephrine and norepinephrine, which are specifically designed to help the body deal with stressful situations. The adrenals control the body's potassium/sodium balance, which is vital for energy production. They also produce sex hormones in minute amounts, which is important for later years when the gonads drop or cease their production.

Anxiety
Apprehension of danger, or dread, accompanied by nervous restlessness, tension, increased heart rate, and shortness of breath unrelated to a clearly identifiable stimulus.

Bile
A bitter, yellow-green secretion of the liver. Bile is stored in the gallbladder and is released when fat enters the first part of the small intestine (duodenum) in order to aid digestion.

Cholesterol
A waxy, fat-like substance manufactured in the liver and found in all tissues, it facilitates the transport and absorption of fatty acids. In foods, only animal products contain cholesterol. An excess of cholesterol in the bloodstream can contribute to the development of atherosclerosis.

Deciliter (dL)
0.1 or one tenth of a liter.

Gallbladder (Gall Bladder)
A small, digestive organ positioned under the liver, which concentrates and stores bile. Problems with the gallbladder often lead to gallbladder attacks, which usually occur after a fatty meal and at night. The following are the most common symptoms: steady, severe pain in the middle-upper abdomen or below the ribs on the right; pain in the back between the shoulder blades; pain under the right shoulder; nausea; vomiting; fever; chills; jaundice; abdominal bloating; intolerance of fatty foods; belching or gas; indigestion.

Hormones (Hormone)
Chemical substances secreted by a variety of body organs that are carried by the bloodstream and usually influence cells some distance from the source of production. Hormones signal certain enzymes to perform their functions and, in this way, regulate such body functions as blood sugar levels, insulin levels, the menstrual cycle, and growth. These can be prescription, over-the-counter, synthetic or natural agents. Examples include adrenal hormones such as corticosteroids and aldosterone; glucagon, growth hormone, insulin, testosterone, estrogens, progestins, progesterone, DHEA, melatonin, and thyroid hormones such as thyroxine and calcitonin.

Liver (Hepatic)
The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.

Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.

Precursor (Precursors)
A biochemical substance, such as an intermediate compound in a chain of enzymatic reactions, from which a more stable or definitive product is formed.

Progesterone
This is the hormone secreted after ovulation by the corpus luteum. It is a steroid (similar to a cholesterol), enters receptive cells to stimulate their growth, and acts as an anabolic agent. Estrogen should be viewed as the primary coat underneath all the cycles during a woman's reproductive years, with progesterone, its antagonist, surging for ten or twelve days in ovulatory months. Most of the actions of progesterone cannot occur without estrogen having previously induced the growth of progesterone-receptive binding sites.

Serotonin
A phenolic amine neurotransmitter (C10H12N2O) that is a powerful vasoconstrictor and is found especially in the brain, blood serum and gastric membranes of mammals. Considered essential for relaxation, sleep, and concentration.

Serum
The cell-free fluid of the bloodstream. It appears in a test tube after the blood clots and is often used in expressions relating to the levels of certain compounds in the blood stream.

Steroid (Steroids)
Any of a large number of hormonal substances with a similar basic chemical structure containing a 17-carbon 14-ring system and including the sterols and various hormones and glycosides.

Stroke (Stroke-Type Event)
A sudden loss of brain function caused by a blockage or rupture of a blood vessel that supplies the brain, characterized by loss of muscular control, complete or partial loss of sensation or consciousness, dizziness, slurred speech, or other symptoms that vary with the extent and severity of the damage to the brain. The most common manifestation is some degree of paralysis, but small strokes may occur without symptoms. Usually caused by arteriosclerosis, it often results in brain damage.

Taurine
A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. May be needed for the proper development and maintenance of the central nervous system. Taurine's role in bile formation is important for fat metabolism and blood cholesterol control.




Last updated: Apr 05, 2009


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