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Low Male Testosterone Level: Overview
A 1996 study reported in the New England Journal of Medicine followed three groups of men. One group was given testosterone and prescribed a strength training program, one group was given testosterone and told not to exercise and one group was just given a training program without testosterone. It was no surprise that the group which exercised on testosterone gained the most muscle and lost the most fat, but the group which took testosterone without exercise actually had greater improvement in muscle and fat composition than the group which trained without it. You can’t build muscle without it!
Causes and Development Some causes of low testosterone levels include congenital problems (such as deficiencies of male hormones and rare malformation syndromes) and acquired problems that include aging, chronic illness, drugs, starvation, stress, head trauma, infections, cancers, surgeries, alcoholism, removal of or trauma to the testicles, and infection or twisting of the testicles in their sac. In addition, certain drugs compete with testosterone in the body.
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Signs, symptoms & indicators of Low Male Testosterone Level:
Conditions that suggest Low Male Testosterone Level:  |  |  |  | | Circulation | Coronary Disease / Heart Attack | Researchers at Columbia University Medical School studied 55 men undergoing X-ray exams of their arteries and found that those with a lower testosterone level had higher degrees of heart disease (blockage of the coronary arteries). This study also found that the protective HDL cholesterol levels were higher in men with higher testosterone levels.
Low testosterone is linked to hypertension, obesity, atherosclerosis and increased waist-to-hip ratio - all of these being heart attack risk factors. Administration of testosterone to men has been reported to decrease the risk factors for heart attack. |
| Hormones |
Low Sex Drive
Progesterone Low or Estrogen Dominance | Testosterone is converted into estrogen naturally. When this conversion is overactive the result is too little testosterone and too much estrogen. High levels of estrogen also trick the brain into thinking that enough testosterone is being produced, thereby reducing the natural production of testosterone. |
| Immunity |
HIV/AIDS | An estimated 45% of men with untreated AIDS and 25% of asymptomatic, untreated HIV-infected men experience low testosterone levels. Both men and women may be negatively affected by testosterone deficiency. |
| Mental |
Depression | Depression can be caused by low levels of certain hormones, including testosterone. |
| Musculo-Skeletal |
Osteoporosis - Osteopenia | Some 30% of men with spinal osteoporosis have long-standing testosterone deficiency, and one-third of men with testosterone deficiency have subnormal bone density that puts them at risk of fractures. |
| Nutrients |
Zinc Requirement | (This relationship of testosterone levels to zinc status does not apply to women.)
Studies support the use of zinc supplementation in the treatment of low sperm count especially in the presence of low testosterone levels. Both sperm count and testosterone levels rose in men with initially low testosterone levels. Zinc status should be evaluated in men with decreased serum testosterone levels. [Nutrition Report, September-October, 1996;14(7): p.52] |
| Uro-Genital |
Andropause/Male Menopause |
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Risk factors for Low Male Testosterone Level:
Low Male Testosterone Level suggests the following may be present:  |  |  |  | | Immunity | HIV/AIDS | An estimated 45% of men with untreated AIDS and 25% of asymptomatic, untreated HIV-infected men experience low testosterone levels. Both men and women may be negatively affected by testosterone deficiency. |
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Low Male Testosterone Level can lead to:
Recommendations and treatments for Low Male Testosterone Level:  |  |  |  | | Botanical | Tribulus | In patients with below-normal serum testosterone levels, physiological levels were reached after treatment with Tribulus. Amongst patients with normal initial levels, the testosterone level was not significantly changed after treatment. |
| Diet |
High/Increased Fat Diet | Extract |
DIM (di-indolmethane)/I3C (Indole-3-Carbinol) | Clinical studies using testosterone injections, creams, or patches have often failed to provide a long-lasting, libido-enhancing effect in aging men. This is because testosterone can be converted to estrogen, which is then taken up by testosterone receptor sites in cells throughout the body. When an estrogen molecule occupies a testosterone receptor site on a cell membrane, it blocks the ability of serum testosterone to induce a healthy hormonal signal. It does not matter how much serum free testosterone is available if excess estrogen is competing for the same cellular receptor sites.
Aromatization is the process of converting testosterone to estrogens. This process increases with age. Aromatase blockers such as DIM and Chrysin can reduce estrogen levels and enhance testosterone levels. If these fail to increase free testosterone and lower excess estradiol, then consider asking your doctor to prescribe the potent aromatase inhibiting drug Arimidex (anastrozole) in the very low dose of 0.5mg, twice per week. Arimidex reduced estradiol by approximately 70% within 24 hours and by approximately 80% after 14 days of daily use.
The usual dose range of DIM for men is 200-400mg per day taken with food. For men involved in a plan of muscular development or fat loss, the dose of bioavailable DIM should be increased to 400-500mg per day. |
| Hormone |
Testosterone | The original and primary use of testosterone is for the treatment of males who have too little or no natural endogenous testosterone production: males with hypogonadism. This hormone replacement therapy helps to maintain serum testosterone levels in the normal range. |
| Lab Tests/Rule-Outs |
Test for Hormones
Testosterone Levels, Test | Unfortunately, there is no general agreement on the threshold of testosterone value below which a man would be considered hypogonadal. In the United States, levels below 200 to 300 pmol/l from a morning sample are generally considered low. |
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KEY | Weak or unproven link: may be a sign or symptom of; may increase risk of; may suggest; sometimes leads to |  | Strong or generally accepted link: is often a sign or symptom of; often suggests; often increases risk of |  | Definite or direct link: is a sign or symptom of; strongly suggests; increases risk of |  | Strong counter-indication: often contraindicates |  | Definitely or absolutely counter-indicates: strongly contraindicates |  | Moderately useful: often helps with |  | Very useful: is highly recommended for |
Last updated: Apr 08, 2012
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